Figure 4. In vitro cyclic GMP response of synthetic peptides.
GC-A (A) or GC-B (B) expressing HEK293 cells were treated with or without10−8 to 10−6 M of proANP, ANP, BNP or CNP for 10 min. *p<0.05 vs no treatment, †p<0.05 vs equimolar dose of BNP, and ‡p<0.05 vs equimolar dose of ANP.