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Predicted and experimental release profile for Timolol from a Timolol-Maleate loaded PCL reservoir device. Device dimensions are 2×3mm rectangle with a 70um thick membrane and 0.4mg Timolol-Maleate (0.3mg Timolol) load. Device was designed using predictive modeling and empirical equations for a 17ug/day Timolol release rate with dimensions appropriate for front of the eye delivery.
