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. Author manuscript; available in PMC: 2015 Sep 13.
Published in final edited form as: Toxicol Lett. 2014 Dec 24;232(3):580–589. doi: 10.1016/j.toxlet.2014.12.015

Fig. 3.

Fig. 3

DIM induces CYP3A4 and MDR1 gene expression in primary human hepatocytes and LS174 T cells: CYP3A4 and MDR1 mRNA expression was analyzed by quantitative RT-PCR in primary human hepatocytes (HU1488, Invitrogen) (A & B) and LS174 T cells (C & D) after treatment with vehicle DMSO, RIF, or increasing concentrations of DIM as indicated for 48 h. Results are presented as fold increase over the untreated control. Data represent mean ± SEM from three independent experiments: *, p < 0.05; compared with the untreated control by unpaired Students t test.