Table 3.
Multivariate Analysis of Grade 2-4 Maximum MTC Grade at Day 2 After BM Donation
| Variable | n | OR | Lower | Upper | p-value |
|---|---|---|---|---|---|
| Median household income in the donor's census block group, 2012a,b |
0.996 | ||||
| 0-25,000 | 78 | 1.00 | |||
| 25,001-50,000 | 721 | 1.01 | 0.51 | 2.00 | 0.985 |
| 50,001-100,000 | 1050 | 0.97 | 0.49 | 1.92 | 0.927 |
| >100,000 | 281 | 0.93 | 0.44 | 1.95 | 0.839 |
| Donor race | 0.821 | ||||
| Non-Hispanic white | 1920 | 1.00 | |||
| Hispanic, all races | 302 | 0.81 | 0.54 | 1.20 | 0.294 |
| Non-Hispanic black | 165 | 0.98 | 0.62 | 1.56 | 0.937 |
| Non-Hispanic Asian/non- Hispanic Pacific Islander |
144 | 1.14 | 0.69 | 1.88 | 0.599 |
| Non-Hispanic other, unknown | 178 | 0.99 | 0.63 | 1.56 | 0.974 |
| Collection center size | 0.068 | ||||
| ≥24 (≥1 every 2 months) | 2138 | 1.00 | |||
| <24 (<1 every 2 months) | 265 | 1.55 | 0.97 | 2.47 | 0.068 |
| Sex | <0.001 | ||||
| Male | 1627 | 1.00 | |||
| Female | 1082 | 2.08 | 1.66 | 2.62 | <0.001 |
| Donor BMI (kg/m2) | 0.029 | ||||
| Normal/underweight (<24.9) | 835 | 1.00 | |||
| Overweight (25-29.9) | 1036 | 0.76 | 0.59 | 0.99 | 0.041 |
| Obese (30+) | 838 | 0.70 | 0.53 | 0.93 | 0.013 |
a
Donors from the centers who provided only non-residential zip codes (e.g. work, university or donor center zip codes) were excluded from the SES analyses.
b
If the census block group could not be located from reported street address, median household income from donor’s zip code was used instead.
Abbreviations: MTC – modified toxicity criteria; BM – bone marrow; OR – odds ratio; BMI – body mass index.