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BNZ132-1-40 (10 μM) inhibits SP in CD4+ and CD8+ T cells. (A) Representative histograms of carboxyfluorescein diacetate succinimidyl ester in CD4+ and CD8+ T cells of one patient with HAM/TSP (HAM5) cultured with or without BNZ132-1-40. (B) Percentage inhibition of SP of CD4+ and CD8+ T cells in three HAM/TSP samples by BNZ132-1-40. (C) Percentage inhibition of Ki-67 expression in CD4+ and CD8+ T-cell subsets from six patients with HAM/TSP.
