Fig. 4.

Structure of the uL10-bL12 stalk region of the BipA–ribosome complex. (A) Cryo-EM density (gray) corresponding to the uL10 and uL11 proteins, as well as the NTD and CTD of bL12 protein. (B) bL12 CTD interaction interface (salmon) with BipA G domain (green). The corresponding cryo-EM reconstitution density map is shown in blue mesh. (C) Ribosomal components of the GTPase-associated center and BipA. Binding of BipA stabilizes the CTD of bL12, part of the dynamic uL10-bL12 stalk, thereby bridging together the GAC components. BipA is colored as in Fig. 1.