Table S3.
Association between differences in brain activity during picture recognition and the L1CAM interactions genetic score that uses the two most significant SNPs per gene
Regional correspondence of the maximum | Left/right | No. of voxels | Peak MNI coordinates | Peak statistics | |||
X | Y | Z | T | Pnominal | |||
Superior frontal cortex (80%) | Left | 76 | −3 | 30 | 40 | −5.77 | 1.1 × 10−8 |
Pars orbitalis cortex (56%), pars triangularis cortex (22%), rostral middle frontal cortex (4%) | Left | 23 | −47 | 41 | −12 | −5.42 | 8.0 × 10−8 |
Pars orbitalis cortex (35%), rostral middle frontal cortex (1%) | Right | 23 | 41 | 44 | −12 | −5.37 | 1.0 × 10−7 |
Lateral orbitofrontal cortex (20%), insula (23%) | Right | 21 | 30 | 22 | 0 | −5.32 | 1.3 × 10−7 |
Superior frontal cortex (84%) | Right | 3 | 11 | 28 | 60 | −5.02 | 6.2 × 10−7 |
The fMRI contrast between previously seen vs. new pictures was used. Only clusters with at least three voxels surviving whole-brain FWE correction are shown (P whole-brain FWE-corrected < 0.05; |T| > 4.77; n = 795). Region names are in accordance with the FreeSurfer nomenclature (71); probabilities are in accordance with the in-house atlas.