Table S4.

Association between differences in brain activity during picture recognition (fMRI contrast of previously seen vs. new pictures) and the percentage of correctly recollected pictures

Regional correspondence of the maximum	Left/right	MNI coordinates at the maximum			T value
		X	Y	Z
Superior frontal cortex (79%), caudal anterior cingulate cortex (2%)	Left	−3	28	40	−12.13
Pars orbitalis cortex (34%), pars triangularis cortex (28%), rostral middle frontal cortex (16%)	Left	−47	44	−8	−9.11
Lateral orbitofrontal cortex (20%), insula (23%)	Right	30	22	0	−9.08
Lateral orbitofrontal cortex (73%), insula (8%)	Left	−28	22	−4	−9.65

Test statistics are shown at the maxima of clusters associated with the L1CAM interactions genetic score (Table 6). They indicate that differences in brain activity at these clusters are also associated with picture recognition performance in the same direction as the L1CAM interactions genetic score. Region names are in accordance with the FreeSurfer nomenclature (71); probabilities are in accordance with the in-house atlas.