Fig. S5.

RIP3 deletion mitigated the inflammatory process. (A) Photographs of wild-type, ApoE single-knockout, and RIP3/ApoE double-knockout mice fed a high-cholesterol diet (1.25%) for 16 wk. (B) H&E-stained histological sections from skin and thymus (arrows indicate cholesterol crystals) and epididymal white adipose tissue (long arrows indicate the infiltrating cells that are most likely macrophages; short arrows indicate the small size of the adipocytes) of wild-type, ApoE single-knockout, and RIP3/ApoE double-knockout mice fed a high-cholesterol diet for 16 wk.