Table 3.
Fold change and statistical behavior of common yc family molecules and related signaling components from gene profiling of isolated microglia and brain mononuclear cells.
| Gene name | Fold change Meth/Ctr | p-value Meth/Ctr | Fold change SIV/Ctr | p-value SIV/Ctr | Fold change SIVMeth/SIV | p-value SIVMeth/SIV |
|---|---|---|---|---|---|---|
| IL2 | 1.13 | 0.76 | 0.54 | 0.13 | 2.17 | 0.41 |
| IL4 | 2.58 | 0.016 | 1.38 | 0.19 | 15.49 | 0.03 |
| IL7 | 1.11 | 0.72 | 1.31 | 0.32 | 6.89 | 0.19 |
| IL7R | 1.72 | 0.12 | 1.64 | 0.23 | 5.3 | 0.049 |
| IL9R | 0.73 | 0.30 | 0.79 | 0.28 | 1.56 | 0.32 |
| IL15 | 1.21 | 0.35 | 2.01 | 0.026 | 4.73 | 0.04 |
| IL15RA | 1.84 | 0.05 | 3.82 | 0.05 | 2.43 | 0.05 |
| IL21 | 1.04 | 0.91 | 0.5 | 0.01 | 1.53 | 0.35 |
| IL21R | 0.98 | 0.91 | 4.16 | 0.19 | 2.76 | 0.18 |
| IL2RG | 2.06 | 0.001 | 4.49 | 0.00005 | 6.71 | 0.0001 |
| ITK | 1.00 | 0.99 | 1.33 | 0.53 | 11.8 | 0.026 |
Values in bold are statistically significant.