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. 2015 Aug 8;5(11):1187–1202. doi: 10.7150/thno.11835

Figure 7.

Figure 7

Endothelial activation mapping unmasks kidney and cerebral inflammation in aged mice. (A) Experimental design. (B) Representative consecutive slices (from a single mouse) from T2*-weighted images of kidneys from young (3 month-old) and aged (18 month-old) mice, after MPIO-αVCAM-1 administration. Yellow squares indicate magnification areas. (C) Corresponding quantification (n=4/group). (D) Representative consecutive slices (from a single mouse) from T2*-weighted images of the brain from young (3 month-old) and aged (18 month-old) mice, after MPIO-αVCAM-1 administration. (E) Corresponding quantification (n=4/group). (F) Schematic representation of the findings in aged mice. *p<0.05 vs young mice.