Table 1. Clinical information and characteristics of study subjects.
| Characteristics | Normalcontrols (n=65) |
Idiopathic PD patients (n = 92) |
||
|---|---|---|---|---|
| Early-stage | Mid-stage | Advanced-stage | ||
| Male/female | 27:38 | 6:8 | 41:18 | 8:11 |
| Age | 59.8 ± 3.7 | 62.9 ± 7.6 | 62.7 ± 7.8 | 62.3 ± 9.2 |
| Hoehn and Yahr score | — | 1.0 ~ 1.5 | 2.0 ~ 2.5 | 3.0 ~ 4.0 |
| Total bilirubin (μmol/L) | — | 9.9 ± 3.6 | 9.9 ± 3.7 | 9.9 ± 3.7 |
| Alkaline phosphatase (U/L) | — | 59.9 ± 14.6 | 59.6 ± 14.5 | 59.6 ± 15.0 |
| AST/SGOT (U/L) | — | 18.3 ± 5.0 | 18.7 ± 5.7 | 18.5 ± 5.2 |
| ALT/SGPT (U/L) | — | 16.2 ± 10.8 | 16.1 ± 10.5 | 15.9 ± 10.2 |
| Gamma GT (U/L) | — | 20.9 ± 10.7 | 20.7 ± 10.6 | 20.7 ± 10.2 |
| Total protein (g/L) | — | 73.4 ± 3.9 | 73.3 ± 3.9 | 73.4 ± 4.0 |
| Albumin (g/L) | — | 43.2 ± 2.5 | 43.2 ± 2.5 | 43.4 ± 2.4 |
| Urea (mmol/L) | — | 5.8 ± 1.4 | 5.8 ± 1.4 | 5.8 ± 1.4 |
| Creatinine (μmol/L) | — | 70.7 ± 13.3 | 70.9 ± 13.3 | 70.4 ± 13.3 |
| Sodium (mmol/L) | — | 139.3 ± 2.3 | 139.3 ± 2.3 | 139.3 ± 2.1 |
| Potassium (mmol/L) | — | 4.0 ± 0.3 | 4.00 ± 0.3 | 4.0 ± 0.3 |
| Chloride (mmol/L) | — | 104.8 ± 2.5 | 104.7 ± 2.5 | 104.7 ± 2.4 |
| HCO3 (mmol/L) | — | 25.4 ± 2.4 | 25.5 ± 2.4 | 25.5 ± 2.4 |
Means ± standard deviation were given for each variable and each group; The classification of patients with different stages of PD was according to Hoehn and Yahr scale rating system.