Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 14;5:14045. doi: 10.1038/srep14045

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

The associations between ATG16L1 expression and prostate cancer aggressiveness were analyzed using MSKCC Prostate Oncogenome data. More advanced prostate cancers with metastasis (A) and high pathologic Gleason score (B) display a tendency toward lower ATG16L1 mRNA expression. Numbers in parentheses indicate the number of patients. (C) ATG16L1 shows higher levels of gene expression in tumors with increased DNA copy number at 2q37. (D) Kaplan-Meier curves of recurrence-free survival according to the downregulation of ATG16L1 expression. Patients were dichotomized with or without ATG16L1 mRNA downregulation (z-scores < −2).