Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Biomaterials. 2015 Feb 23;52:79–87. doi: 10.1016/j.biomaterials.2015.02.016

Table 1.

Table of culture parameter adjustments

Observation Adjustment
PPA too high or too low Decrease or increase PA flow rate
Perfusate not draining from PV cannula Adjust PV cannula
Significant atelectasis Increase I:E or breath size (distance between POC-Upper and POC-Lower)
Little visible motion during ventilation Increase breath size or make breaths longer (reduce RR)
Lung deflates before POC-Upper is reached Decrease POC-Upper or increase I:E
Over-inflation Decrease breath size, decrease I:E, make breaths shorter (increase RR), or increase POC-Lower (bring closer to 0)
Under-inflation Increase breath size, increase I:E, make breaths longer (decrease RR), or decrease POC-Lower