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. Author manuscript; available in PMC: 2016 Mar 10.
Published in final edited form as: Nature. 2015 Sep 2;525(7568):206–211. doi: 10.1038/nature15251

Extended Data Figure 9. TCGA RNA expression profile analysis.

Extended Data Figure 9

a-f. TCGA RNA expression profile of GOF p53 target genes (top), housekeeping genes (middle), and WT p53 target genes (bottom) in (a) brain lower grade glioma, (b) head and neck squamous cell carcinoma, (c) bladder urothelial carcinoma, (d) colon adenocarcinoma, (e) esophageal carcinoma, or (f) pancreatic adenocarcinoma tumors with WT p53 (blue), GOF p53 (orange), or p53 null (white). Expression values are normalized read counts ((a), (b), (c), (d) and (f)), or RPKM values (e) from TCGA RNA-seq datasets. Mann-Whitney tests were performed to compute significance.