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. 2015 Aug 24;112(36):11324–11329. doi: 10.1073/pnas.1509968112

Fig. S8.

Fig. S8.

Role of USP25 in virus-triggered noncanonical NF-κB pathways. (A and B) USP25 deficiency had no effect on SeV- or HSV-1–triggered accumulation of NIK or p52 in BMDCs. Wild-type and Usp25−/− BMDCs were infected with SeV or HSV-1 followed by immunoblot with the indicated antibodies. (C) H3K4me3 and H3K9me3 of the Ifnb promoter in wild-type and Usp25−/− BMDCs. Wild-type and Usp25−/− BMDCs were left uninfected or infected with SeV or HSV-1 for 8 h followed by ChIP analysis with the indicated antibodies. Data are representative of three (A and B) or two (C) independent experiments. Graphs show means and SD of four replicates. **P < 0.01, ***P < 0.001.