Table 1.
Anthropomorphic and metabolic characteristics | Young subjects (n = 15) | Elderly subjects (n = 15) | P value |
Age (years) | 27 ± 2 | 69 ± 1 | |
BMI (kg/m2) | 23.3 ± 0.5 | 24.5 ± 0.5 | NS |
Lean body mass (%) | 56.6 ± 1.9 | 54.5 ± 2.5 | NS |
Activity (miles/d) | 3.9 ± 0.5 | 3.2 ± 0.4 | NS |
IMCL (%) | 0.80 ± 0.10 | 1.38 ± 0.22 | <0.04 |
Insulin sensitivity index (ISI) | 5.4 ± 0.3 | 4.1 ± 0.3 | 0.007 |
Fasting plasma glucose (mmol/L) | 4.9 ± 0.1 | 5.4 ± 0.4 | 0.020 |
Fasting plasma insulin (μU/mL) | 9 ± 1 | 10 ± 1 | NS |
Plasma leptin (ng/mL) | 5.8 ± 1.0 | 6.2 ± 1.1 | NS |
Plasma HMW adiponectin (μg/mL) | 7.5 ± 0.9 | 9.8 ± 1.0 | NS |
Plasma C-reactive protein (μg/mL) | 0.56 ± 0.23 | 1.06 ± 0.62 | NS |
Rates of basal whole body energy expenditure (kcal/24 h) | 1,670 ± 52 | 1,423 ± 48 | <0.002 |
Fasting RQ | 0.77 ± 0.02 | 0.82 ± 0.02 | <0.05 |