Table 4.
The haplotypes of two SNPs (rs3734805 and rs2046210) and risk of breast cancer (adjusted by age, and BMI)
| Haplotype | Freq. | Case-Control Ratio Counts | Case-Control Frequencies | χ2 | p a | OR (95% CI) | p b |
|---|---|---|---|---|---|---|---|
| AC | 0.606 | 653.2:466.8, 731.2:434.8 | 0.583, 0.627 | 4.615 | 0.032* | 1 | --- |
| CT | 0.316 | 385.2:734.8, 338.2:827.8 | 0.344, 0.290 | 7.654 | 0.006* | 1.31 (1.08-1.58) | 0.006* |
| AT | 0.068 | 69.8:1050.2, 84.8:1081.2 | 0.062, 0.073 | 0.973 | 0.324 | 1.06 (0.75-1.50) | 0.74 |
| CC | 0.01 | 11.8:1108.2, 11.8:1154.2 | 0.011, 0.010 | 0.012 | 0.914 | 0.98 (0.36-2.67) | 0.97 |
SNPs: Single nucleotide polymorphisms.
p for Chi-square test.
OR: Odds ratio. CI: Confidence interval.
p for logistic regression adjusted by BMI and age.
p < 0.05 indicates statistical significance.