Table 1.
SNP genotype across the TARDBP gene on chromosome 1p36.22
| SNP | C hr | Position | Risk allele | Genotype | |
|---|---|---|---|---|---|
| Family A/II-2 | Family B/II-1 | ||||
| rs1925666 | 1 | 10999600 | A | AG | AA |
| rs6656310 | 1 | 11002488 | T | TT | TT |
| rs1281008 | 1 | 11011002 | G | AG | GG |
| rs11121663 | 1 | 11024395 | T | CT | TT |
| rs2003046 | 1 | 11032827 | C | AC | AC |
| rs12059717 | 1 | 11043485 | C | CC | CC |
| rs9430161 | 1 | 11046855 | G | GT | GT |
| rs6704113 | 1 | 11053101 | A | AA | AA |
| rs11121675 | 1 | 11060075 | T | GT | TT |
| rs11121676 | 1 | 11063043 | C | CC | CC |
| rs3765896 | 1 | 11074420 | A | AG | AA |
| rs2273348 | 1 | 11079077 | C | CT | CC |
| rs1033638 | 1 | 11086717 | C | CT | CC |
| rs12711521 | 1 | 11090916 | A | AC | AA |
| rs7548659 | 1 | 11107439 | T | GT | TT |
| rs12121344 | 1 | 11111629 | C | CC | CC |
| rs2802211 | 1 | 11132217 | A | AG | AA |
| rs2536 | 1 | 11166713 | T | TT | TT |
| rs2275525 | 1 | 11169676 | G | GG | GG |
| rs1057079 | 1 | 11205058 | A | AG | AA |
| rs7540001 | 1 | 11243833 | A | AA | AA |
| rs1074078 | 1 | 11326788 | C | CT | CC |
| rs3010223 | 1 | 11372638 | A | AG | AA |
| rs2982373 | 1 | 11377114 | G | AG | GG |
| rs909836 | 1 | 11398365 | C | CT | CT |
| rs10864498 | 1 | 11409469 | G | AG | AG |
| rs2982364 | 1 | 11432744 | C | CC | CT |
| rs2788557 | 1 | 11439588 | G | GG | AG |
| rs3010208 | 1 | 11444975 | T | TT | CT |
| rs6660541 | 1 | 11447805 | G | GG | AG |
| rs6685668 | 1 | 11447850 | C | CC | CC |
| rs12058244 | 1 | 11456027 | G | GG | GG |
| rs6671983 | 1 | 11461601 | G | GG | AG |
| rs10864504 | 1 | 11476203 | G | GG | AG |
| rs877309 | 1 | 11489678 | G | GG | AG |
| rs10864508 | 1 | 11490744 | T | TT | GT |
| rs2922240 | 1 | 11493832 | C | CC | CT |
| rs2379151 | 1 | 11494573 | G | GG | AG |
| rs7414229 | 1 | 11498299 | T | TT | TT |
| rs11806225 | 1 | 11499286 | T | TT | TT |
| rs3124627 | 1 | 11508016 | A | AA | AG |
| rs12026602 | 1 | 11518397 | T | TT | CT |
| rs11121742 | 1 | 11520653 | T | TT | GT |
| rs12046038 | 1 | 11525533 | A | AA | AA |
| rs17036930 | 1 | 11531918 | C | CC | CC |
| rs2007215 | 1 | 11537977 | G | GG | AG |
| rs7555562 | 1 | 11542957 | A | AA | AC |
| rs17036947 | 1 | 11575260 | G | GG | GG |
| rs3887379 | 1 | 11577831 | T | TT | TT |
| rs2072996 | 1 | 11578973 | A | AA | AA |
| rs2076469 | 1 | 11584164 | T | TT | TT |
| rs2076468 | 1 | 11589911 | C | CC | CC |
| rs2235660 | 1 | 11595331 | C | CC | CT |
| rs2817621 | 1 | 11601119 | T | TT | TT |
| rs11808316 | 1 | 11619154 | C | CC | CC |
| rs2817581 | 1 | 11622979 | C | CC | CC |
| rs2745285 | 1 | 11626858 | A | AA | AA |
| rs2745275 | 1 | 11645598 | C | CC | CC |
| rs7530509 | 1 | 11654491 | G | GG | GG |
The Risk allele column is the previously identified Sardinian founder risk haplotype across this locus as published in Chiò et al.9
The Genotype columns show the single-nucleotide polymorphism data for the probands of Family A and Family B.
The shared allele is highlighted in bold.