Table 1.

Neuropsychological test battery and self-rated questionnaires administered at baseline and 24 months

Neuropsychological test battery: Memory: Word list learning test (WLL) [16] with delayed recall, Wechsler memory scale-revised (WMS-R) logical memory (LM) I and II [17], and the modified Rey-Osterrieth (mR-O) figure immediate and delayed recall [18] Attention/psychomotor speed: WMS-R digit span forward, trail making test part A [19], and Wechsler adult intelligence scale-revised (WAIS-R) digit symbol [20] Visuospatial ability: modified WAIS-R block design and copy of the mR-O figure Language abilities: Boston naming test [21] and semantic fluency (animals) [22] Executive functions: Trail making test part B, WMS-R digit span backward, letter fluency (F,A,S), clock drawing, and WAIS-R digit symbol Self-rated questionnaires: Structured interview to assess subjective memory abilities [23] Activities of daily living (ADLs) and instrumental ADLs [24], [25] Center for Epidemiological Studies-Depression (CES-D) [26], [27] Structured interview documenting self-reported prescription and over-the-counter (OTC) medications