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. 2015 Jun 8;19(9):2067–2074. doi: 10.1111/jcmm.12613

Table 1.

Selected reports on the impact of bacteria on stem cells

Biological impact Cell populations Bacterial species Experimental model Reference
Cell viability DFPCs P. gingivalis Treatment with LPS 47
PDLSCs P. gingivalis Treatment with LPS 53
DFPCs, BMSCs P. gingivalis Treatment with LPS 78
USSCs Undefined Treatment with LPS and flagellin 79
DPSCs S. mutans Treatment with LPS 80
Differentiation DFPCs P. gingivalis Treatment with LPS 47
BMSCs E. coli Treatment with LPS 52
PDLSCs P. gingivalis Treatment with LPS 53
USSCs Undefined Treatment with LPS and flagellin 79
DPPCs A.actinomyce-temcomitans Treatment with LPS 87
DPSCs P. gingivalis Treatment with LPS 88
Immunomodulation DFPCs P. gingivalis Treatment with LPS 47
BMSCs P. gingivalis, F. nucleatum, A.actinomyce-temcomitans Co-culture model 69
DFPCs, BMSCs P. gingivalis, F. nucleatum Co-culture model 70
DFPCs, BMSCs P. gingivalis Treatment with LPS 78
USSCs Undefined Treatment with LPS and flagellin 79
ESC-ECs Undefined Treatment with LPS and C12-iE-DAP 99
DFSCs, DPSCs Undefined Treatment with LPS 100
AMSCs S. typhimurium, L. acidophilus Co-culture model 101
DPSCs P. gingivalis, E. coli, P. endodontalis Treatment with LPS 102
DPSCs Undefined Treatment with LPS 103
MSCs Undefined Polymicrobial model of sepsis 104

Stem cells: AMSCs, adipose-derived mesenchymal stem cells; BMSCs, bone marrow stem cells; DFPCs, dental follicle progenitors cells; DPPCs, dental pulp progenitor cells; DPSCs, dental pulp stem cells; ESC-ECs, human embryonic stem cell-derived endothelial cells; MSCs, mesenchymal stem cells; PDLSCs, periodontal ligament stem cells; USSCs, unrestricted somatic stem cells. Bacteria: A. actinomycetemcomitans, Aggregatibacter actinomycetemcomitans; E. coli, Escherichia coli; F. Prausnitzii, Faecalibacterium prausnitzii; L. acidophilus, Lactobacillus acidophilus; P. endodontalis, Porphyromonas endodontalis; P. gingivalis, Porphyromonas gingivalis; S. mutans, Streptococcus mutans; S. typhimurium, Salmonella typhimurium.