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. 2015 Jul 29;14(5):896–906. doi: 10.1111/acel.12376

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© 2015 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig 4 — Neuronal loss or gain of CycD/Cdk4 induces cell death. (A) Graph quantifying death in adult laminar neurons from the following genotypes (* indicates P < 0.05, ***P < 0.001). (B) Adult male central nervous system (CNS) expressing ELAV-GFP/+ for 2 days, (C) Adult male CNS expressing ELAV-CycD/Cdk4 for 2 days (white arrow heads pointed at dead cells, which stain denser), (D) adult male expressing ELAV-GFP/+ for 14 days, (E) ELAV-CycD/Cdk4 for 14 days, (F) graph quantifying death in laminar neurons in mutants (***P < 0.001). (G) Precise excision (PE) control at 2 days, (H) cycD mutants at 2 days, (I) PE control at 14 days, (J) cycD mutants at 14 days; other images in Supporting Information.