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. 2015 Sep 14;10(9):e0138121. doi: 10.1371/journal.pone.0138121

Fig 3. CFT073 ΔdsdA colonizes the murine urinary tract indistinguishably from wild type.

Fig 3

(A) CFT073 ΔdsdA and CFT073 ΔlacZYA were co-inoculated at a 1:1 ratio into CBA/J mice (n = 17). Bacteria from bladder and kidney homogenates were enumerated on MacConkey’s medium plus lactose. Lines are drawn at the geometric mean relative competitive index (RCI). Nine mice had no detectable bacteria in their kidneys. Statistical Significance was assessed by a Wilcoxon signed-rank test relative to a hypothetical RCI of 1. (B) Manipulations were carried out as described for panel A except that single strains were used (n = 16 for each). Two mice infected with CFT073 had no detectable bacteria in their kidneys and three mice infected with CFT073 ΔdsdA had no detectable bacteria in their kidneys. Lines are drawn at the geometric mean CFU/organ. Statistical significance was assessed by the Mann-Whitney U test.