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. 2015 Sep 14;10(9):e0138099. doi: 10.1371/journal.pone.0138099

Table 5. Results of multivariate logistic regression analysis for the association between HCY and six inflammatory/immune items.

Quartile of items
Q1 Q2 Q3 Q4
HCY vs C3
Model 1 1 1.017 (0.748, 1.382) 1.234 (0.908, 1.678) 0.917 (0.673, 1.249)
Model 2 1 1.021 (0.750, 1.390) 1.207 (0.886, 1.645) 0.868 (0.635, 1.186)
Model 3 1 0.983 (0.720, 1.341) 1.136 (0.823, 1.567) 0.808 (0.574, 1.137)
HCY vs C4
Model 1 1 0.859 (0.639, 1.155) 0.980 (0.731, 1.314) 0.771 (0.572, 1.037)
Model 2 1 0.805 (0.596, 1.086) 0.887 (0.858, 1.196) 0.703 (0.519, 0.951)
Model 3 1 0.801 (0.592, 1.084) 0.874 (0.645, 1.185) 0.696 (0.509, 0.951)
HCY vs CRP
Model 1 1 1.233 (0.919, 1.653) 1.043 (0.777, 1.401) 1.205 (0.899, 1.617)
Model 2 1 1.165 (0.866, 1.566) 0.901 (0.665, 1.220) 1.088 (0.807, 1.467)
Model 3 1 1.149 (0.850, 1.553) 0.877 (0.640, 1.203) 1.069 (0.776, 1.473)
HCY vs IgA
Model 1 1 0.985 (0.733, 1.344) 0.935 (0.687, 1.273) 1.077 (0.792, 1.465)
Model 2 1 0.966 (0.706, 1.322) 0.911 (0.667, 1.243) 1.047 (0.768, 1.428)
Model 3 1 0.972 (0.711, 1.330) 0.899 (0.657, 1.228) 1.029 (0.752, 1.409)
HCY vs IgG
Model 1 1 1.248 (0.923, 1.688) 0.917 (0.676, 1.244) 1.034 (0.763, 1.403)
Model 2 1 1.269 (0.935, 1.722) 0.967 (0.710, 1.316) 1.065 (0.783, 1.450)
Model 3 1 1.263 (0.930, 1.715) 0.959 (0.702, 1.309) 1.057 (0.773, 1.445)
HCY vs IgM
Model 1 1 1.427 (1.052, 1.936) 1.248 (0.922, 1.690) 1.227 (0.904, 1.665)
Model 2 1 1.446 (1.061, 1.970) 1.304 (0.959, 1.772) 1.270 (0.932, 1.731)
Model 3 1 1.447 (1.062, 1.973) 1.294 (0.951, 1.760) 1.269 (0.929, 1.734)

The levels of six inflammatory/immune items were divided into quartile (Q1<levels of 25%, 25%≤Q2≤50%, 50%<Q3≤75%, Q4>75%).

Model 1: unadjusted; Model 2: adjust for age; Model 3: adjust for age, smoking status, alcoholic drinking, BMI, WHR.

HCY = homocysteine; BMI = Body Mass Index; WHR = waist hip rate; C3 = Complement C3; C4 = Complement C4; CRP = C reactive protein; Ig = Immunoglobulin.