Table 1. PAD2 Steady-State Kinetics and Calcium Dependence with the Substrate BAEE^a.

^aN-α-benzoyl-l-arginine ethyl ester.

^bColor coding refers to residue location mapped on the holoPAD2 structure (right).

^cND = Not determined.

^dFunction is inferred from comparing PAD2 residues to corresponding residues in PAD4 complexed with N-α-benzoyl-l-arginine amide (PDB: 1WDA).

^eThe k_cat/K_M for these compounds was determined using the equation v = k_cat/K_M([E_t][S]), when possible.