Table 1.
Expression of αvβ5 and α5β1 integrins and CAR after treatment with chemotherapeutics†
| Positive cell (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| αvβ5 | α5β1 | CAR | |||||||
| Control | Gem | 5‐FU | Control | Gem | 5‐FU | Control | Gem | 5‐FU | |
| Capan1 | 0.85 | 1.08 | 3.41 | 11.41 | 23.63 | 34.58 | 3.12 | 1.15 | 4.76 |
| PANC‐1 | 12.75 | 22.80 | 17.23 | 57.96 | 58.89 | 61.46 | 51.90 | 92.00 | 85.90 |
| HS766t | 1.11 | 1.42 | 2.42 | 2.13 | 3.91 | 7.24 | 0.73 | 0.31 | 0.44 |
| MIA Paca‐2 | 1.98 | 19.38 | 8.38 | 10.97 | 90.93 | 45.43 | 2.95 | 14.84 | 12.96 |
†Data are presented as the percentage of surface marker‐positive cells after each treatment. FU, fluorouracil; Gem, gemcitabine.