Table 1. Baseline characteristics in 34 patients undergoing MitraClip procedure, of whom 9 experienced MACE.
Events | Non-Events | p-value | |
---|---|---|---|
Number | 9 | 25 | n/a |
Age [years] | 79.6 (8.6) | 79.4 (6.7) | 0.95 |
Hypertension [%] | 78 | 80 | 0.73 |
Hyperlipidemia [%] | 67 | 64 | 0.96 |
Type 2 Diabetes [%] | 33 | 24 | 0.92 |
Current or former smoker [%] | 33 | 20 | 0.77 |
Male Sex [%] | 56 | 52 | 0.84 |
Known CHD [%] | 89 | 84 | 0.85 |
NYHA Classification [%] | 0.86 | ||
III | 33 | 36 | |
III-IV | 33 | 24 | |
IV | 33 | 40 | |
Degree of insufficiency (1–3) Median | 3 | 3 | 0.96 |
Left-ventricular ejection fraction [%] | 0.30 | ||
Above 50% | 33 | 68 | |
Between 30%-50% | 56 | 28 | |
Below 30% | 11 | 4 | |
Atrial Fibrillation [%] | 67 | 48 | 0.57 |
Etiology of Mitral Insufficiency [%] | 0.12 | ||
Degenerative | 56 | 88 | |
Functional | 44 | 12 | |
Logistic Euro Score [%] | 0.15 | ||
Mean | 27.8 (19.4) | 16.9 (16.5) | |
Median | 26.8 [12.3; 41.7] | 11.9 [6.8; 21.6] | |
STS-Score [%] | 0.06 | ||
Mean Risk for Mortality | 17.1 (11.0) | 11.1 (7.3) | |
Median Risk for Mortality | 14.3 [12.0; 22.6] | 9.9 [5.8; 12.7] | |
NT-proBNP [pg/mL] | 0.0004 | ||
Mean | 12,705 (10,702) | 2,168 (1,602) | |
Median | 11,251 [3619; 19137] | 1,974 [1051; 2940] | |
MR-proANP [pmol/L] | 0.0001 | ||
Mean | 757.1 (298.2) | 330.37 (127.66) | |
Median | 755.6 [570.2; 800.6] | 318.30 [261.4; 387.2] | |
Hs-TnT [ng/L] | 0.0047 | ||
Mean | 267.5 (534.8) | 36.55 (33.3) | |
Median | 92.6 [38.0; 155.5] | 25.20 [16.4; 48.7] | |
Hs-CRP [mg/L] | 0.0334 | ||
Mean | 37.6 (66.9) | 6.8 (7.6) | |
Median | 14.6 [4.3; 32.0] | 5.5 [1.5; 8.3] | |
Cystatin C [mg/L] | 0.0112 | ||
Mean | 2.2 (0.7) | 1.5 (0.6) | |
Median | 2.1 [1.7; 2.6] | 1.4 [1.2; 1.7] | |
Galectin-3 [ng/mL] | 0.0007 | ||
Mean | 37.4 (14.0) | 19.2 (9.7) | |
Median | 34.8 [26.1; 48.1] | 16.6 [12.9; 20.6] | |
SST-2 [ng/mL] | 0.0025 | ||
Mean | 119.9 (116.4) | 37.3 (20.6) | |
Median | 75.1 [52.7; 134.8] | 29.4 [24.9; 43.6] |