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. 2015 Sep 14;10(9):e0137464. doi: 10.1371/journal.pone.0137464

Table 1. Baseline characteristics in 34 patients undergoing MitraClip procedure, of whom 9 experienced MACE.

Events Non-Events p-value
Number 9 25 n/a
Age [years] 79.6 (8.6) 79.4 (6.7) 0.95
Hypertension [%] 78 80 0.73
Hyperlipidemia [%] 67 64 0.96
Type 2 Diabetes [%] 33 24 0.92
Current or former smoker [%] 33 20 0.77
Male Sex [%] 56 52 0.84
Known CHD [%] 89 84 0.85
NYHA Classification [%] 0.86
III 33 36
III-IV 33 24
IV 33 40
Degree of insufficiency (1–3) Median 3 3 0.96
Left-ventricular ejection fraction [%] 0.30
Above 50% 33 68
Between 30%-50% 56 28
Below 30% 11 4
Atrial Fibrillation [%] 67 48 0.57
Etiology of Mitral Insufficiency [%] 0.12
Degenerative 56 88
Functional 44 12
Logistic Euro Score [%] 0.15
Mean 27.8 (19.4) 16.9 (16.5)
Median 26.8 [12.3; 41.7] 11.9 [6.8; 21.6]
STS-Score [%] 0.06
Mean Risk for Mortality 17.1 (11.0) 11.1 (7.3)
Median Risk for Mortality 14.3 [12.0; 22.6] 9.9 [5.8; 12.7]
NT-proBNP [pg/mL] 0.0004
Mean 12,705 (10,702) 2,168 (1,602)
Median 11,251 [3619; 19137] 1,974 [1051; 2940]
MR-proANP [pmol/L] 0.0001
Mean 757.1 (298.2) 330.37 (127.66)
Median 755.6 [570.2; 800.6] 318.30 [261.4; 387.2]
Hs-TnT [ng/L] 0.0047
Mean 267.5 (534.8) 36.55 (33.3)
Median 92.6 [38.0; 155.5] 25.20 [16.4; 48.7]
Hs-CRP [mg/L] 0.0334
Mean 37.6 (66.9) 6.8 (7.6)
Median 14.6 [4.3; 32.0] 5.5 [1.5; 8.3]
Cystatin C [mg/L] 0.0112
Mean 2.2 (0.7) 1.5 (0.6)
Median 2.1 [1.7; 2.6] 1.4 [1.2; 1.7]
Galectin-3 [ng/mL] 0.0007
Mean 37.4 (14.0) 19.2 (9.7)
Median 34.8 [26.1; 48.1] 16.6 [12.9; 20.6]
SST-2 [ng/mL] 0.0025
Mean 119.9 (116.4) 37.3 (20.6)
Median 75.1 [52.7; 134.8] 29.4 [24.9; 43.6]