Table 2.
Demographics and baseline measures for 92 participants of the DASH-Sodium trial overall and by diet assignment.
| Total (N=92) | Control (N=44) | DASH (N=48) | P value | |
|---|---|---|---|---|
| Age, yr (SD) | 46.0 (10.2) | 45.8 (11.1) | 46.2 (9.4) | 0.86 |
| Men, N (%) | 34 (37.0) | 15 (34.1) | 19 (39.6) | 0.59 |
| Black, N (%) | 60 (65.2) | 31 (70.5) | 29 (60.4) | 0.31 |
| Household income | ||||
| ≤60,000/year, N (%) | 67 (74.4) | 35 (81.4) | 32 (68.1) | 0.15 |
| Education | ||||
| Some college or less, N (%) | 49 (53.9) | 23 (53.5) | 26 (54.2) | 0.97 |
| Alcohol, N (%) | ||||
| ≤7 drinks/week | 91 (99.0) | 44 (100) | 47 (97.9) | 0.09 |
| SBP mmHg, mean (SD) | 133.6 (9.7) | 134.5 (10.4) | 132.8 (9.1) | 0.4 |
| DBP mmHg, mean (SD) | 84.6 (4.6) | 85.0 (3.5) | 84.3 (5.5) | 0.48 |
| Hypertension* (yes) | 34 (37.0) | 15 (34.1) | 19 (39.6) | 0.59 |
| Weight, baseline, kg, mean (SD) | 87.6 (16.8) | 89.9 (18.2) | 85.5 (15.2) | 0.22 |
| BMI, kg/m2, mean (SD) | 30.4 (5.5) | 31.2 (6.0) | 29.7 (5.0) | 0.2 |
| Phosphorus, mg/dl, mean (SD) | 3.2 (0.5) | 3.1 (0.5) | 3.2 (0.5) | 0.46 |
| Intact PTH, pg/ml, mean (SD) | 45.7 (17.8) | 47.2 (16.9) | 44.2 (18.7) | 0.43 |
| Creatinine, mg/dl, mean (SD) | 1.0 (0.2) | 1.0 (0.2) | 1.04 (0.2) | 0.41 |
| eGFR ml/min/1.73m2, mean (SD) | 84.5 (18.0) | 86.8 (18.9) | 82.4 (16.9) | 0.24 |
| eGFR range: | 0.9 | |||
| >90, N (%) | 31 (34) | 15 (34) | 16 (33) | |
| 75-89, N (%) | 33 (36) | 17 (39) | 16 (33) | |
| 60-74, N (%) | 20 (22) | 9 (20) | 11(23) | |
| <60, N (%) | 8 (9) | 3 (9) | 5 (10) | |
| Albuminuria† (yes), N (%) | 7 (8) | 5 (11) | 2 (4) | 0.19 |
| CKD‡ (yes), N (%) | 12 (13.0) | 6 (13.6) | 6 (12.5) | 0.87 |
| CKD Stage: | 0.1 | |||
| Stage 1, eGFR ≥ 90, N (%) | 1 (1.1) | 0 (0) | 1 (2.1) | |
| Stage 2, eGFR 60-89, N (%) | 3 (3.3) | 3 (6.8) | 0 (0) | |
| Stage 3, eGFR <60, N (%) | 8 (8.7) | 3 (6.8) | 5 (10.4) |
*
Hypertension defined as SBP ≥140 mmHg or DBP ≥90 mmHg.
†
Albuminuria defined as urine albumin-to-creatinine ratio ≥17 mg/g for men and ≥25 mg/g for women.
‡
CKD defined as eGFR less than 60 ml/min/1.73 m2 or presence of albuminuria at any eGFR.
SBP, systolic blood pressure; DBP, diastolic blood pressure; PTH, parathyroid hormone; CKD, chronic kidney disease; BMI, body mass index; eGFR, estimated glomerular filtration rate