Table 2. Conservation of predicted miRNAs involved in development-related signaling pathways.
Organism | Signaling pathway | Number of conserved miRNAs with D. magna | Total number of known miRNAs | % Conserved with D. magna * |
---|---|---|---|---|
Homo sapiens | Calcium | 18 | 48 | 37.50 |
Hedgehog | 23 | 45 | 51.11 | |
WNT | 41 | 104 | 39.42 | |
Notch | 24 | 49 | 48.98 | |
Chemokine | 37 | 88 | 42.05 | |
Total | 52 | 145** | 35.86 | |
Calcium | 11 | 36 | 30.56 | |
Hedgehog | 11 | 24 | 45.83 | |
Mus musculus | WNT | 11 | 36 | 30.56 |
Notch | 7 | 16 | 43.75 | |
Chemokine | 12 | 34 | 35.29 | |
Total | 18 | 52** | 34.62 |
*Number of conserved miRNAs with D. magna /Total number of signal pathway miRNAs.
**Total number is achieved after removal of overlapping miRNAs among signaling pathways.