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. 2015 Sep 14;10(9):e0137743. doi: 10.1371/journal.pone.0137743

Table 3. Univariate and multivariate analyses of clinical variables and quantitative metabolic parameters for disease-free survival.

Variables Univariate analysis Multivariate analysis
HR 95% CI P HR 95% CI P
Age (years) <45 vs. ≥45 1.030 0.6–4.2 0.310
Primary tumor SUVmax >12.3 vs. ≤12.3 0.673 0.5–4.0 0.412
Primary tumor MTV >63.7 cm3 vs. ≤63.7 cm3 2.172 0.8–5.6 0.141
Primary tumor TLG >411.9 vs. ≤411.9 2.294 0.8–5.8 0.130
Nodal SUVmax >4.7 vs. ≤4.7 7.592 1.8–34.8 0.006 4.158 1.1–22.7 0.041
Nodal MTV >10.3 cm3 vs. ≤10.3 cm3 6.015 1.3–9.2 0.014
Nodal TLG >32.9 vs. ≤32.9 6.266 1.3–9.4 0.012
FIGO stage >IIB vs. IIB 1.695 0.7–5.2 0.193
Tumor size ≥4 cm vs. <4 cm 0.811 0.5–5.1 0.368
Paraaortic node metastases 5.393 1.2–8.5 0.020
Post-treatment response PR or PD vs. CR 13.289 2.4–17.0 <0.001 7.162 1.5–11.3 0.007

SUVmax = maximum standardized uptake value; MTV = whole-body metabolic tumor volume; TLG = total lesion glycolysis; FIGO = International Federation of Gynecology and Obstetrics; CR = complete response; PR = partial response; PD = progressive disease; HR = hazard ratio; CI = confidence interval.