Table 1. PMN cytotoxicity of canonical and noncanonical lukotoxin subunit EC50 (nM).
S subunit | F subunit | ||||
---|---|---|---|---|---|
LukF-PV | HlgB | LukD | LukB | Luk AB copurified | |
LukS-PV | 0.4±0.16 | 0.1±0.03 | >233.33 | >133.3 | |
HlgA | 1.7±0.96 | 1.5±0.86 | 3.6±1.2 | >133.3 | |
LukE | 11.5±4.3 | 11.26±3.1 | 15.4±2.9 | >133.3 | |
HlgC | 2.0±0.1 | 3.0±0.2 | 63.0±6.9 | >133.3 | |
LukA | >133.3 | >133.3 | >133.3 | 108±2.1 | |
Luk AB copurified | 8.1±0.96 |