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. 2015 Sep 14;10(9):e0137908. doi: 10.1371/journal.pone.0137908

Fig 4. Two domains IPR000421 and IPR000115 (Panels A and B, respectively) exemplify the effect of sample size on the domain promiscuity definition.

Fig 4

Domain A shows a decrease in promiscuity depending on the number of strains used for calculation. Domain B has a stable promiscuity, independent of the number of strains used for calculation. Panel C shows a graphical illustration of the concept of absolute promiscuity. In this cartoon, domain A is absolutely promiscuous as it has always the same neighbouring partners, which is not the case of domain B.