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. 2015 Sep 14;10(9):e0137908. doi: 10.1371/journal.pone.0137908

Table 1. Top 10 more promiscuous domains with respect to the number of different neighbouring domains.

InterPro Identifier Average domain count InterPro description
IPR027417 141 P-loop containing nucleoside triphosphate hydrolase
IPR003439 92 ABC transporter-like
IPR011527 32 ABC transporter type 1, transmembrane domain
IPR001564 15 Nucleoside diphosphate kinase
IPR008334 12 5'-Nucleotidase, C-terminal
IPR029052 12 Metallo-dependent phosphatase-like
IPR026459 11 Ribonucleotide reductase, class 1b, subunit NrdE
IPR009078 8 Ferritin-like superfamily
IPR026023 8 Ribonucleotide reductase small subunit, prokaryotic
IPR001645 7 Folylpolyglutamate synthetase