Table 2. Top 10 least promiscuous domains with respect to the number of different neighbouring domains.
| InterPro Identifier | Average domain count | InterPro description |
|---|---|---|
| IPR000120 | < 1 | Amidase |
| IPR000191 | < 1 | DNA glycosylase/AP lyase |
| IPR000192 | < 1 | Aminotransferase class V domain |
| IPR001093 | < 1 | IMP dehydrogenase/GMP reductase |
| IPR001342 | < 1 | Homoserine dehydrogenase, catalytic |
| IPR001518 | < 1 | Argininosuccinate synthase |
| IPR001754 | < 1 | Orotidine 5'-phosphate decarboxylase domain |
| IPR001986 | < 1 | Enolpyruvate transferase domain |
| IPR003733 | < 1 | Thiamine phosphate synthase |
| IPR004188 | < 1 | Phenylalanine-tRNA ligase, class II, N-terminal |