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. 2015 Sep 14;10(9):e0137908. doi: 10.1371/journal.pone.0137908

Table 3. Top 10 more promiscuous domains with respect to the number of different metabolic pathways they appear in.

InterPro Identifier Number of pathways domain occurs in InterPro description
IPR001564 10 Nucleoside diphosphate kinase
IPR027417 9 P-loop containing nucleoside triphosphate hydrolase
IPR026456 5 Glycosyltransferase AglJ
IPR013785 4 Aldolase-type TIM barrel
IPR012162 4 Polyribonucleotide nucleotidyltransferase
IPR011268 4 Purine nucleoside phosphorylase
IPR004468 4 CTP synthase
IPR009078 4 Ferritin-like superfamily
IPR026023 4 Ribonucleotide reductase small subunit, prokaryotic
IPR004402 4 Purine nucleoside phosphorylase DeoD-type