Fig 1. Liver/body weight ratio from pair-fed mice with either ethanol (EtOH, n = 12) or control chow (ctrl, n = 12) is shown (Fig 1A).

The ratio of plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is presented (Fig 1B). Fig 1C represents the shed blood volume in mL that was removed for the induction and maintenance of hemorrhagic shock in either ctrl-fed or EtOH-fed vehicle (veh)-treated or D-JNKI-1-treated mice. H/R denotes hemorrhage with subsequent resuscitation. Sham operated animals underwent the same surgical procedures but H/R was not carried out. *: p <0.05 vs. ctrl. Fig 1D demonstrates the mean arterial blood pressure (MAP) before and during the hemorrhagic shock as well as during and after the resuscitation (n = 7–12). *: p <0.05 ctrl-veh vs. EtOH-veh.