Fig 3. Exercise prevented the impairment of object recognition memory resulting from low doses of arsenic exposure.

Mice were administered arsenic and underwent swimming exercise daily for 12 weeks and were subsequently trained in the object recognition memory task. Long-term memory was tested 24 h later. (A) Exercise had no effect on the exploration time in mice treated with 3 mg/ kg arsenic when exploring two identical objects (p > 0.05). (B) Exercise increased the exploration time to novel object in mice treated with 3 mg/ kg arsenic (p < 0.05). (C, D) Exercise had no effect on the exploration time in mice treated with 10 mg/ kg arsenic when exploring two identical objects or exploring two different objects (both p > 0.05). The data were expressed as the mean ± SEM (n = 14 per group). *p < 0.05, compared with exploring time to object A1.