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. 2015 Sep 14;10(9):e0137978. doi: 10.1371/journal.pone.0137978

Fig 3. Granuloma scores.

Fig 3

The granuloma scores were obtained by counting the numbers of granulomata individually at 100 × magnification. Each data point represented average number of granulomata from 10 microscopic fields from H&E stained lung section from one mouse. A: The granuloma scores in the pigeon dropping extract(PDE)-challenged mice. The scores on days 7 and 10 were significantly increased compared with days 0 and 2. B: The granuloma scores on day 10 in the saline-treated mice and the PDE-challenged mice, with and without interleukin(IL)-17A antibody-administration. The score in the PDE-challenged mice was significantly increased compared with that of the saline-treated mice (P < 0.001), and the score in the PDE-challenged mice subjected to anti-IL-17A antibody administration was significantly decreased compared with the PDE-challenged mice (P = 0.021). The data are presented as the means ± standard errors of the mean (SEs) for each group (day 0–10: n = 7–11, control group: n = 10, PDE group: n = 11, anti-IL-17A group: n = 8). *: P < 0.05, **: P < 0.01, ***: P < 0.001.