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(A) Colony formation of MCF-7 cells after exposure to compounds 1, 2 and 5 (10 μmol/L) for 3 or 24 h. Cisplatin was included as a positive control. (B) Colony formation after exposure to compound 1 (10 μmol/L) for 3, 5, 12 and 24 h. Bar charts show the percentage of counted colonies relative to control untreated cells and represent the mean±SD of 3 independent experiments. *p < 0.05 versus control cells.
