Table 1. Cytotoxicity of the iron complexes and the corresponding ligands against MCF-7 and CAPAN-1 cells.
| IC50 (μM) a | ||
|---|---|---|
| Cell line | ||
| Compound | MCF-7 | CAPAN-1 |
| 1-Fe | 17.5 ± 0.9 | >100 |
| 1 | 7.4 ± 0.2 | 9.9 ± 1.01 |
| 2-Fe | >100 | >100 |
| 2 | 3.7 ± 0.4 | 6.0 ± 0.7 |
| 3-Fe | 63.5 ± 2.1 | >100 |
| 3 | 40.6 ± 2.5 | 27.7 ± 2.9 |
| 4-Fe | 73.5 ± 0.7 | >100 |
| 4 | 88.5 ± 0.7 | 32.0 ± 10.4 |
| 5-Fe | >100 | >100 |
| 5 | 7.7 ± 0.3 | 7.9 ± 0.5 |
| Cisplatin | 2.4 ± 0.4 | 2.2 ± 0.3 |
aThe IC50 values were determined by the MTT assay after 48 h of compound exposure. Data represents the mean ± SD of at least three independent experiments made in triplicates.