Table 3. Incidence and adjusted hazard ratio for coronary heart diseases stratified by comorbidity for the fibromyalgia cohort and compared with the non-fibromyalgia cohort.

	Fibromyalgia			Reference
Characteristics	Event	PY	Rate	Event	PY	Rate	IRR (95% CI)	Adjusted HR † (95% CI)
Diabetes
No	6,457	502,818	12.8	11,945	1,545,637	7.73	1.66(1.62–1.70)**	1.51(1.46–1.56)**
Yes	1,823	41,810	43.6	3,217	92,556	34.8	1.25(1.17–1.34)**	1.29(1.22–1.37)**
Hypertension
No	3,898	449,503	8.67	7,561	1,419,868	5.33	1.63(1.59–1.67)**	1.59(1.53–1.66)**
Yes	4,382	95,125	46.1	7,601	218,326	34.8	1.32(1.27–1.38)**	1.34(1.29–1.39)**
Hyperlipidemia
No	5,587	473,821	11.8	11,315	1,509,897	7.49	1.57(1.54–1.61)**	1.50(1.45–1.55)**
Yes	2,693	70,808	38.0	3,847	128,297	30.0	1.27(1.20–1.34)**	1.35(1.29–1.42)**
Congestive heart failure
No	7,982	540,580	14.8	14,615	1,629,147	8.97	1.65(1.61–1.68)**	1.48(1.44–1.52)**
Yes	298	4,049	73.6	547	9,047	60.5	1.22(1.02–1.46)*	1.25(1.08–1.44)*
Cerebral vascular diseases
No	6,812	509,627	13.4	12,994	1,572,683	8.26	1.62(1.58–1.66)**	1.47(1.43–1.52)**
Yes	1,468	35,002	41.9	2,168	65,511	33.1	1.27(1.17–1.37)**	1.40(1.31–1.50)**
Depression
No	7,872	527,718	14.9	14,754	1,613,888	9.14	1.63(1.60–1.67)**	1.46(1.42–1.50)**
Yes	408	16,911	24.1	408	24,305	16.8	1.44(1.25–1.65)**	1.67(1.45–1.90)**
Anxiety
No	7,294	508,421	14.35	14,162	1,595,256	8.88	1.62(1.58–1.65)**	1.47(1.43–1.51)**
Yes	986	36,208	27.23	882	44,312	19.9	1.37(1.24–1.51)**	1.57(1.43–1.72)**

PY, person-year; Rate, incidence rate (per 1,000 person-years); IRR, incidence rate ratio; HR, hazard ratio

^†Adjusted HR: multiple analysis after adjusting for age, gender, occupation, income and comorbidities

*p<0.05

**p<0.001