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. Author manuscript; available in PMC: 2016 Sep 11.
Published in final edited form as: J Mol Biol. 2015 Apr 3;427(18):2904–2911. doi: 10.1016/j.jmb.2015.03.017

Figure 2.

Figure 2

Cartoon illustrations of symmetric Hsp90 conformations observed without clients and asymmetric complexes with clients. Structural asymmetry in client complexes was made apparent from recent EM analyses of Hsp902:Cdc37:Cdk439 and Hsp902:Hop:Hsp70:GR28; 30.