Table 4.

Multivariate Adjusted OR (95% CI) of Cardiovascular Risk Factors Associated with Inflammation and Endothelial Dysfunction Biomarkers

Biomarkers (levels)	Hypertension	Dyslipidemia	Hyperglycemia	Overweight or Obesity	Central Obesity
hsCRP, mg/L
<3.95	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
3.95–11.38	1.32 (1.05, 1.66)	0.98 (0.81, 1.19)	0.80 (0.62, 1.03)	1.87 (1.48, 2.39)	1.82 (1.48, 2.25)
>11.38	1.96 (1.52, 2.53)	2.33 (1.85, 2.94)	2.95 (2.27, 3.83)	3.27 (2.50, 4.27)	3.34 (2.62, 4.26)
Trend P value	<0.001	<0.001	<0.001	<0.001	<0.001
sE-selectin, ng/mL
<14.78	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
14.78–24.83	1.40 (1.13, 1.73)	1.12 (0.94, 1.35)	1.39 (1.11, 1.74)	1.11 (0.89, 1.37)	1.14 (0.94, 1.39)
>24.83	1.35 (1.05, 1.72)	1.24 (1.00, 1.54)	1.09 (0.83, 1.43)	2.10 (1.64, 2.67)	1.82 (1.45, 2.29)
Trend P value	0.013	0.048	0.291	<0.001	<0.001
Angiotensin II, pg/mL
<40.0	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
40.0–71.3	1.26 (1.01, 1.57)	0.96 (0.79, 1.16)	1.50 (1.18, 1.91)	0.85 (0.69, 1.06)	1.00 (0.82, 1.21)
>71.3	1.81 (1.40, 2.33)	0.86 (0.69, 1.08)	1.17 (0.88, 1.56)	0.93 (0.72, 1.19)	1.05 (0.83, 1.33)
Trend P value	<0.001	0.189	0.306	0.543	0.683
sICAM-1, ng/mL
<230.96	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
230.96–426.78	1.03 (0.83, 1.29)	1.05 (0.87, 1.27)	1.24 (0.96, 1.59)	0.99 (0.79, 1.23)	0.92 (0.75, 1.12)
>426.78	1.29 (0.96, 1.73)	1.70 (1.30, 2.22)	2.80 (2.06, 3.80)	1.36 (1.02, 1.82)	1.23 (0.86, 1.48)
Trend P value	0.126	0.001	<0.001	0.070	0.557

Note. The multivariate model included biomarkers groups, age, gender, current smoking, current drinking, family history of CVD, hypertension, hyperglycemia, dyslipidemia, overweight or obesity, and central obesity. The three levels of all the biomarkers were categorized as the low/up quartiles: <25%, 25%–75%, and >75%.