Table 3. Central Corneal Thickness Before and After the Administrations of Ripasudil in Instilled Eye.
SD = standard deviation. Values are the central corneal thickness (μm) examined by Pentacam Scheimpflug topography.
| Subject | Day 0 | Day 7 | Follow-up | ||||
|---|---|---|---|---|---|---|---|
| Pre a | 1.5 hrs. | 6 hrs. | 0 hr b | 1.5 hrs. | 6 hrs. | ||
| 1 | 559 | 550 | 556 | 558 | 555 | 555 | 555 |
| 2 | 559 | 575 | 569 | 564 | 561 | 561 | 564 |
| 3 | 587 | 575 | 575 | 568 | 566 | 575 | 580 |
| 4 | 560 | 554 | 556 | 558 | 559 | 554 | 567 |
| 5 | 558 | 553 | 559 | 554 | 556 | 555 | 562 |
| 6 | 561 | 559 | 555 | 561 | 562 | 561 | 559 |
| Mean | 564.0 | 561.0 | 561.7 | 560.5 | 559.8 | 560.2 | 564.5 |
| SD | 11.3 | 11.2 | 8.3 | 5.0 | 4.1 | 7.9 | 8.6 |
a Before the administration of ripasudil.
b Before the final administrations of ripasudil (Twelve hours after administration).