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. 2015 Sep 14;10(9):e0136891. doi: 10.1371/journal.pone.0136891

Table 1. Numbers of metabolites confirmed and putatively identified in cell extracts and spent media.

Cell extracts Spent media
Confirmed(std, MS/MS) Putative Confirmed(std, MS/MS) Putative
Metabolites after filteringlipids and peptides 153 (135, 18) 459 137 (119, 18) 548
2-fold difference frominitial medium na na 79 (63, 16) 173
No change from initialmedium na na 58 (56, 2) 375
No clear speciesspecificity 48 (43, 5) 222 21 (18, 3) 53
Clear species specificity (>2-fold change) 105 (92, 13) 237 58 (45, 13) 120
Clear species specificity(>3-fold change) 64 (55, 9) 161 43 (32, 11) 87
Clear species specificity(> 4-fold change) 52 (45, 7) 129 39 (30, 9) 68

Key: na, not applicable; std, using standards; the data on species specificity for the spent media are for the metabolites (79 confirmed, 173 putative) showing at least 2-fold differences from the initial medium.