Skip to main content
. 2015 Sep 14;10(9):e0136891. doi: 10.1371/journal.pone.0136891

Table 2. Metabolites of confirmed to MSI level 1 in promastigote extracts that differed by at least 3-fold in intensity between two species.

Metabolite Mass Ldon/Lmaj Ldon/Lmex Lmaj/Lmex
Glycine 75.0321 2.73 4.25 1.56
Serine 105.0426 1.69 4.44 2.63
Glycerate 106.0266 22.11 16.78 0.76
Imidazole-4-acetaldehyde 110.0480 4.93 2.11 0.43
Cytosine 111.0433 12.66 6.63 0.52
Proline 115.0634 0.22 0.12 0.57
Threonine 119.0583 8.49 2.13 0.25
Nicotinate 123.0320 0.79 0.11 0.14
Imidazole-4-acetate 126.0428 1.11 0.12 0.11
5-Oxoproline 129.0428 1.43 7.47 5.23
Pipecolate 129.0789 1.28 0.09 0.07
3-Methy2-oxopentanoic acid/4-Methy2-oxopentanoic acid 130.0631 0.59 2.90 4.90
trans-4-Hydroxy-proline 131.0582 2.63 3.32 1.26
Asparagine 132.0534 2.35 3.05 1.30
*Deoxyribose 134.0580 3.15 7.37 2.34
Homocysteine 135.0353 1.61 5.68 3.53
Hypoxanthine 136.0385 5.15 0.37 0.07
Ethanolamine phosphate 141.0192 1.87 0.23 0.12
2-Oxoglutarate 146.0216 1.95 5.97 3.07
O-Acetyserine 147.0532 2.28 3.17 1.39
*Ribose 150.0529 2.67 4.90 1.84
Xanthine 152.0335 16.91 0.21 0.01
*Xylitol 152.0686 4.76 3.73 0.78
Orotate 156.0172 0.29 0.12 0.43
Imidazole lactic acid 156.0535 4.72 2.06 0.44
proline carbamate 158.0690 9.18 2.62 0.29
N-acetyl valine 159.0894 18.61 39.95 2.15
N-gamma-Acetyldiaminobutyrate 160.0847 9.35 3.98 0.43
O-Acetyhomoserine 161.0689 16.70 1.52 0.09
Carnitine 161.1051 7.89 1.50 0.19
D3-phenyllactate 166.0631 3.42 8.28 2.42
3-(3-Hydroxy-phenyl)-propanoic acid 166.0632 4.14 11.59 2.80
N-Acetyleucine 173.1053 8.76 5.47 0.62
Citrulline 175.0957 5.18 2.45 0.47
*Sorbitol 182.0793 8.26 3.05 0.37
N-Acetylglutamine 188.0795 1.66 4.92 2.97
Gulonate 196.0585 2.41 30.95 12.83
Indole-3-lactate 205.0741 4.01 2.93 0.73
Deoxyuridine 228.0748 INF INF 0.00
Ribose 5-phosphate 230.0192 0.75 4.92 6.57
Cystine 240.0240 4.06 1.31 0.32
Uridine 244.0696 2.11 3.47 1.64
p-aminobenzoyl glutamate 266.0904 INF 15.50 0.00
N-(Arginino)succinate 290.1228 16.71 0.39 0.02
Glutathione 307.0841 3.62 1.03 0.28
Ribose 1,5-bisphosphate 309.9858 0.12 4.27 36.62
GMP 363.0586 4.15 1.93 0.47

Key: Ldon, intensity in L. donovani extract; Lmaj, intensity in L. major extract; Lmex, intensity in L. mexicana extract.

* Matches retention time of standard but ability of the method to separate all the isomeric possibilities not established.