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. 2015 Sep 14;10(9):e0137728. doi: 10.1371/journal.pone.0137728

Table 1. Reaction rate constants of major enzymes for the CCM pathway in human erythrocytes [17].

Enzyme Value of K
Hexokinase 9.96 × 101 h −1
Glucose 6-phosphate isomerase 9.56 × 103 h −1
Phosphofructokinase1 (PFK1) 5.81 × 105 h −1
Aldolase 1.03 × 106 h −1
Triosephosphate isomerase 7.30 × 104 h −1
Glyceraldehyde phosphate isomerase 9.06 × 103 h −1
Phosphoglycerate kinase 6.68 × 103 h −1
Diphosphoglycerate mutase 3.44 × 103 h −1
Diphosphoglycerate phosphatase 2.6 × 100 h −1
Phosphoglycerate mutase 3.90 × 105 h −1
Enolase 7.95 × 104 h −1
Pyruvate kinase 2.69 × 102 h −1
Lactate dehydrogenase 1.02 × 101 h −1
Adenylate kinase 7.50 × 103 h −1
ATPase 3.56 × 10−1 h −1
Glutathione oxidation 3.00 × 10−2 h −1
Glutathione reductase 7.53 × 103 h −1
Glucose 6-phosphate dehydrogenase 3.88 × 103 h −1
6-phosphogluconate dehydrogenase 2.86 × 103 h −1
Ribose phosphate epimerase 3.77 × 104 h −1
Ribose phosphate isomerase 2.51 × 103 h −1
Phosphorybosylpyrophosphate synthetase 8.71 × 104 h −1
Transketolase1 1.68 × 100 h −1
Transaldolase 1.2 × 101 h −1
Transketolase2 6.01 × 101 h −1