Table 1.

List of different types of TLR with causal organisms

Causal organism		Type of TLR	References
Bacteria	Pseudomonas aeruginosa	TLR 9 silencing involved in reducing neutrophil infiltration	Huang et al. (2005)
		Endotoxin of PA involved in TLR4-dependent expression of PECAM-1 and MIP-2	Khatri et al. (2002)
		Flagellin of PA involved in TLR5–NF-Kβ pathway for corneal inflammation	Zhang et al. (2004a)
		TLR4 involved in host resistance during Pseudomonas aeruginosa keratitis	Huang et al. (2006)
	Staphylococcus aureus	Corneal inflammation mediated by TLR2 and MyD88 in resident epithelial cells	Sun et al. (2006)
		TLR2-dependent recognition of bacteria peptidoglycan	Dziarski and Gupta (2005)
		TLR 2 role in bacterial endophthalmitis	Kumar et al. (2010)
	Streptococcus pneumoniae	TLR2 and 4-associated host–bacterial interaction	Bourcier et al. (2005)
	Endosymbiotic Wolbachia	TLR 4-linked inflammatory response	Saint Andre et al. 2002
Protozoan	Acanthamoeba	TLR4-stimulated inflammatory responses in the cornea	Alizadeh et al. (2014)
Fungi	Aspergillus fumigatus	TLR2-associated cytokine and chemokine production	Guo et al. (2012)
		TLR2 and TLR4 initiate immune responses	Guo and Wu (2009)
	Candida albicans	TLR2, but not TLR4, triggers cytokine production	Gil and Gozalbo (2006)
Virus	Herpes simplex virus-1	Toll-like receptor 3 agonist poly (I:C)-induced antiviral response in human corneal epithelial cells	Kumar et al. (2006a)
		Induce TLR3, 9 and IL-6 secretion, involved in corneal cell inflammation	Hayashi et al. (2006)
		Induce expression of cytokines, interferon and TLR7 in HCEC	Li et al. (2006)
	Human adenovirus	Empty viral capsid involved in TLR 4-linked keratitis	Chintakuntlawar et al. (2010)