Table 1.
Baseline clinical characteristics
| Characteristic | Ivabradine | Bisoprolol | P |
|---|---|---|---|
| Age (years), mean ± SD | 70 ± 7 | 68 ± 7 | ns |
| Gender (women), n (%) | 10 (33) | 11 (37) | ns |
| BMI (kg/m2), mean ± SD | 23.6 ± 4,2 | 24.1 ± 4,1 | ns |
| Hypertension, n (%) | 20 (66) | 18 (62) | ns |
| Diabetes, n (%) | 4 (13) | 4 (14) | ns |
| Smoking, n (%) | 7 (23) | 7 (24) | ns |
| Dyslipidemia, n (%) | 14 (46) | 12 (41) | ns |
| Previous MI, n (%) | 7 (23) | 6 (21) | ns |
| Previous revascularization, n (%) | 10 (33) | 11 (38) | ns |
| Exertional angina, n (%) | 11 (36) | 9 (31) | ns |
| SBP (mmHg), mean ± SD | 126 ± 11 | 129 ± 14 | ns |
| DBP (mmHg), mean ± SD | 74 ± 7 | 77 ± 8 | ns |
| Resting heart rate (bpm), mean ± SD | 73 ± 10 | 71 ± 9 | ns |
| LVEF (%), mean ± SD | 58 ± 6 | 60 ± 5 | ns |
BMI Body mass index, bpm Beats per minute, DBP Diastolic blood pressure, LVEF Left ventricular ejection fraction, MI Myocardial infarction, ns Not significant, SBP Systolic blood pressure, SD Standard deviation