Table 5.
Adverse effects in included studies
| Study ID | Adverse effects of (number of cases) |
|
| Chemo group | Combination group | |
| DcLi2009L (Li et al., 2009) | None | Fever, headache |
| DcZhong2011L (Zhong et al., 2011) | Anemia (6), leucopenia (13), nausea (13), fever (3), rash, acne, pruritus (1), fatigue (8), febrile neutropenia (1) | Anemia (4), leucopenia (10), nausea (9), fever (10), rash, acne, pruritus (9), fatigue (1), febrile neutropenia (0) |
| DcYuan2011L (Yuan et al., 2011a) | Fever (2), chill (2) | Fever (11), chill (8), shock (1) |
| DcSheng2011L (Sheng et al., 2011) | Arrest of bone-marrow, gastrointestinal reactions | Fever (1), arrest of bone-marrow, gastrointestinal reactions |
| DcZhang2011C (Zhang et al., 2011) | ||
| DcYuan2011C (Yuan et al., 2011b) | None | Fever (2) |
| DcZhu2011C (Zhu et al., 2011) | None | Fever (2) |
| DcLi2012C (Li et al., 2012) | Arrest of bone-marrow, gastrointestinal reactions, peripheral neurotoxicity | Fever (1), arrest of bone-marrow, gastrointestinal reactions, peripheral neurotoxicity |
| DcRen2013B (Ren et al., 2013) | Vomiting (1), diarrhea (1), hepatic complications (2) | Neuritis (1), vomiting (9), diarrhea (12), hepatic complications (4) |
| DcYuan2013L (Yuan et al., 2013) | Anemia, skin petechiae, fatigue, oral pain, constipation, peripheral neuropathy | Fever, anemia, skin petechiae, fatigue, oral pain, constipation, peripheral neuropathy |
| DcNi2013B (Ni et al., 2013) | None | Fever (3) |
| DcGao2014G (Gao et al., 2014) | None | Fever (9) |
None: no adverse effects